Intolerant voor gluten, tarwe of toch iets anders?

In dit vierde deel van de reeks over voedselintoleranties stellen we je voor aan een hoofdrolspeler: gluten. Coeliakie is de goed beschreven vorm van glutenintolerantie, terwijl de pathologie rond niet-coeliakische glutengevoeligheid in een waas van mysterie en scepticisme dwaalt. Toch valt er veel over te vertellen en komen de puzzelstukjes langzaam op hun plaats. Andere bestanddelen van tarwe en dysbiose zijn zulke puzzelstukjes.

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Auteur

Joost Meeusen

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Referenties

  1. Biesiekierski JR. What is gluten? J Gastroenterol Hepatol. 2017 Mar;32 Suppl 1:78-81.
  2. Besser HA, Khosla C. Celiac disease: mechanisms and emerging therapeutics. Trends Pharmacol Sci. 2023; 44(12):949-962.
  3. Sabença C, Ribeiro M, Sousa T, et al. Wheat/Gluten-Related Disorders and Gluten-Free Diet Misconceptions: A Review. Foods. 2021; 10(8).
  4. Singla D, Malik T, Singh A, et al. Advances in understanding wheat-related disorders: A comprehensive review on gluten-free products with emphasis on wheat allergy, celiac and non-celiac gluten sensitivity. Food Chem Adv. 2024; 4:100627.
  5. Hadjivassiliou M, Croall ID, Zis P, et al. Neurologic Deficits in Patients With Newly Diagnosed Celiac Disease Are Frequent and Linked With Autoimmunity to Transglutaminase 6. Clin Gastroenterol Hepatol. 2019 Dec;17(13):2678-2686.e2.
  6. Floare ML, Wharton SB, Simpson JE, et al. Cerebellar degeneration in gluten ataxia is linked to microglial activation. Brain Commun. 2024 Mar 7;6(2):fcae078.
  7. Bianchi PI, Lenti MV, Petrucci C, et al. Diagnostic Delay of Celiac Disease in Childhood. JAMA Netw Open. 2024 Apr 1;7(4):e245671.
  8. Caio G, Volta U, Sapone A, et al. Celiac disease: a comprehensive current review. BMC Med. 2019 Jul 23;17(1):142.
  9. Raiteri A, Granito A, Giamperoli A, et al. Current guidelines for the management of celiac disease: A systematic review with comparative analysis. World J Gastroenterol. 2022; 28(1):154-175.
  10. Aziz I, Evans KE, Papageorgiou V, et al. Are patients with coeliac disease seeking alternative therapies to a gluten-free diet? J Gastrointestin Liver Dis. 2011; 20(1):27-31︎.
  11. Abdi F, Zuberi S, Blom JJ, et al. Nutritional Considerations in Celiac Disease and Non-Celiac Gluten/Wheat Sensitivity. Nutrients. 2023; 15(6).
  12. Shewry PR, Hey SJ. The contribution of wheat to human diet and health. Food Energy Secur. 2015 Oct;4(3):178-202.
  13. Vici G, Belli L, Biondi M, et al. Gluten free diet and nutrient deficiencies: A review. Clin Nutr. 2016 Dec;35(6):1236-1241.
  14. Nestares T, Martín-Masot R, Flor-Alemany M, et al. Influence of Ultra-Processed Foods Consumption on Redox Status and Inflammatory Signaling in Young Celiac Patients. Nutrients. 2021; 13(1).︎
  15. Aguayo-Patrón SV, Calderón de la Barca AM. Old Fashioned vs. Ultra-Processed-Based Current Diets: Possible Implication in the Increased Susceptibility to Type 1 Diabetes and Celiac Disease in Childhood. Foods. 2017 Nov 15;6(11):100.
  16. Hallert C, Svensson M, Tholstrup J, et al. Clinical trial: B vitamins improve health in patients with coeliac disease living on a gluten-free diet. Aliment Pharmacol Ther. 2009; 29(8):811-6.
  17. Drabińska N, Krupa-Kozak U, Abramowicz P, et al. Beneficial Effect of Oligofructose-Enriched Inulin on Vitamin D and E Status in Children with Celiac Disease on a Long-Term Gluten-Free Diet: A Preliminary Randomized, Placebo-Controlled Nutritional Intervention Study. Nutrients. 2018 Nov 15;10(11):1768.
  18. Drabińska N, Jarocka-Cyrta E, Złotkowska D, et al. Daily oligofructose-enriched inulin intake impacts bone turnover markers but not the cytokine profile in pediatric patients with celiac disease on a gluten-free diet: Results of a randomised, placebo-controlled pilot study. Bone. 2019 May;122:184-192.
  19. Feruś K, Drabińska N, Krupa-Kozak U, et al. A Randomized, Placebo-Controlled, Pilot Clinical Trial to Evaluate the Effect of Supplementation with Prebiotic Synergy 1 on Iron Homeostasis in Children and Adolescents with Celiac Disease Treated with a Gluten-Free Diet. Nutrients. 2018 Nov 21;10(11):1818.
  20. Mozafarybazargany M, Khonsari M, Sokoty L, et al. The effects of probiotics on gastrointestinal symptoms and microbiota in patients with celiac disease: a systematic review and meta-analysis on clinical trials. Clin Exp Med. 2023 Oct;23(6):2773-2788.
  21. Seiler CL, Kiflen M, Stefanolo JP, et al. Probiotics for Celiac Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Am J Gastroenterol. 2020 Oct;115(10):1584-1595.
  22. Bernardo D, Martínez-Abad B, Vallejo-Diez S, et al. Ascorbate-dependent decrease of the mucosal immune inflammatory response to gliadin in coeliac disease patients. Allergol Immunopathol (Madr). 2012; 40(1):3-8.︎
  23. Engström N, Böhn L, Josefsson A, et al. Development of celiac-safe foods: prevention of transglutaminase 2 (TG2) deamidation of gluten in healthy non-celiac volunteers. Front Nutr. 2024; 11:1308463.
  24. Delvecchio M, Bizzoco F, Lapolla R, et al. Iodine Absorption in Celiac Children: A Longitudinal Pilot Study. Nutrients. 2021 Mar 1;13(3):808.
  25. Di Stefano M, Miceli E, Mengoli C, et al. The Effect of a Gluten-Free Diet on Vitamin D Metabolism in Celiac Disease: The State of the Art. Metabolites. 2023 Jan 2;13(1):74.
  26. Expósito Miranda M, García-Valdés L, Espigares-Rodríguez E, et al. Non-celiac gluten sensitivity: Clinical presentation, etiology and differential diagnosis. Gastroenterol Hepatol. 2023; 46(7):562-571.
  27. Aziz I, Lewis NR, Hadjivassiliou M, et al. A UK study assessing the population prevalence of self-reported gluten sensitivity and referral characteristics to secondary care. Eur J Gastroenterol Hepatol. 2014 Jan;26(1):33-9.
  28. Crawley C, Savino N, Halby C, et al. The effect of gluten in adolescents and young adults with gastrointestinal symptoms: a blinded randomised cross-over trial. Aliment Pharmacol Ther. 2022; 55(9):1116-1127.
  29. Roncoroni L, Bascuñán KA, Vecchi M, et al. Exposure to Different Amounts of Dietary Gluten in Patients with Non-Celiac Gluten Sensitivity (NCGS): An Exploratory Study. Nutrients. 2019 Jan 10;11(1):136.
  30. Borrelli DE, Andreis F, Schiepatti A, et al. Is it time to rethink the burden of non-coeliac gluten sensitivity? A systematic review. Minerva Gastroenterol (Torino). 2022; 68(4):442-449.
  31. Hollon J, Puppa EL, Greenwald B, et al. Effect of gliadin on permeability of intestinal biopsy explants from celiac disease patients and patients with non-celiac gluten sensitivity. Nutrients. 2015; 7(3):1565-76.
  32. Bucci C, Zingone F, Russo I, et al. Gliadin does not induce mucosal inflammation or basophil activation in patients with nonceliac gluten sensitivity. Clin Gastroenterol Hepatol. 2013; 11(10):1294-1299.e1.
  33. Rostami K, Ensari A, Marsh MN, et al. Gluten Induces Subtle Histological Changes in Duodenal Mucosa of Patients with Non-Coeliac Gluten Sensitivity: A Multicentre Study. Nutrients. 2022; 14(12).
  34. Rotondi Aufiero V, Fasano A, Mazzarella G. Non-Celiac Gluten Sensitivity: How Its Gut Immune Activation and Potential Dietary Management Differ from Celiac Disease. Mol Nutr Food Res. 2018; 62(9):e1700854.
  35. van Megen F, Skodje GI, Lergenmuller S, et al. A Low FODMAP Diet Reduces Symptoms in Treated Celiac Patients With Ongoing Symptoms-A Randomized Controlled Trial. Clin Gastroenterol Hepatol. 2022 Oct;20(10):2258-2266.e3.︎
  36. Lusetti F, Schiepatti A, Scalvini D, et al. Efficacy of a Low-FODMAP Diet for Coeliac Patients with Persistent IBS-like Symptoms despite a Gluten-Free Diet: A Systematic Review. Nutrients. 2024 Apr 8;16(7):1094.
  37. Fernandes Dias LBA, Kobus RA, Bagolin do Nascimento A. Effectiveness of the low-FODMAP diet in improving non-celiac gluten sensitivity: a systematic review. Br J Nutr. 2022 Nov 3:1-9.
  38. Skodje GI, Sarna VK, Minelle IH, et al. Fructan, Rather Than Gluten, Induces Symptoms in Patients With Self-Reported Non-Celiac Gluten Sensitivity. Gastroenterology. 2018;154:529-539.e2︎.
  39. Gibson PR, Muir JG, Newnham ED. Other Dietary Confounders: FODMAPS et al. Dig Dis. 2015;33(2):269-276.︎
  40. Nordin E, Hellström PM, Dicksved J, et al. Effects of FODMAPs and Gluten on Gut Microbiota and Their Association with the Metabolome in Irritable Bowel Syndrome: A Double-Blind, Randomized, Cross-Over Intervention Study. Nutrients. 2023; 15(13).
  41. Mumolo MG, Rettura F, Melissari S, et al. Is Gluten the Only Culprit for Non-Celiac Gluten/Wheat Sensitivity? Nutrients. 2020; 12(12).︎
  42. Leccioli V, Oliveri M, Romeo M, et al. A New Proposal for the Pathogenic Mechanism of Non-Coeliac/Non-Allergic Gluten/Wheat Sensitivity: Piecing Together the Puzzle of Recent Scientific Evidence. Nutrients. 2017; 9(11).
  43. Armandi A, Bespaljko H, Mang A, et al. Short-term reduction of dietary gluten improves metabolic-dysfunction associated steatotic liver disease: A randomised, controlled proof-of-concept study. Aliment Pharmacol Ther. 2024 May;59(10):1212-1222.
  44. Ul Haq MR. Gluten Exorphins. 2020; in: Opioid Food Peptides. Springer, Singapore. https://doi.org/10.1007/978-981-15-6102-3_6︎
  45. Lionetti E, Leonardi S, Franzonello C, et al. Gluten Psychosis: Confirmation of a New Clinical Entity. Nutrients. 2015; 7(7):5532-9.
  46. Rotondi Aufiero V, Fasano A, Mazzarella G. Non-Celiac Gluten Sensitivity: How Its Gut Immune Activation and Potential Dietary Management Differ from Celiac Disease. Mol Nutr Food Res. 2018; 62(9):e1700854.
  47. Dieterich W, Schuster C, Gundel P, et al. Proteins from Modern and Ancient Wheat Cultivars: Impact on Immune Cells of Healthy Individuals and Patients with NCGS. Nutrients. 2022; 14(20).
  48. Kasarda DD. Can an increase in celiac disease be attributed to an increase in the gluten content of wheat as a consequence of wheat breeding? J Agric Food Chem. 2013 Feb 13;61(6):1155-9.
  49. Saadati S, Sadeghi A, Mohaghegh-Shalmani H, et al. Effects of a gluten challenge in patients with irritable bowel syndrome: a randomized single-blind controlled clinical trial. Sci Rep. 2022; 12(1):4960.︎
  50. Arabpour E, Alijanzadeh D, Sadeghi A, et al. Gluten restriction in irritable bowel syndrome, yes or no?: a GRADE-assessed systematic review and meta-analysis. Front Nutr. 2023 Nov 1;10:1273629.
  51. Londei M, Ciacci C, Ricciardelli I, et al. Gliadin as a stimulator of innate responses in celiac disease. Mol Immunol. 2005 May;42(8):913-8.
  52. de Graaf MCG, Lawton CL, Croden F, et al. The effect of expectancy versus actual gluten intake on gastrointestinal and extra-intestinal symptoms in non-coeliac gluten sensitivity: a randomised, double-blind, placebo-controlled, international, multicentre study. Lancet Gastroenterol Hepatol. 2024 Feb;9(2):110-123.
  53. Asri N, Rostami-Nejad M, Anderson RP, et al. The Gluten Gene: Unlocking the Understanding of Gluten Sensitivity and Intolerance. Appl Clin Genet. 2021; 14:37-50.
  54. Dunne MR, Byrne G, Chirdo FG, et al. Coeliac Disease Pathogenesis: The Uncertainties of a Well-Known Immune Mediated Disorder. Front Immunol. 2020; 11:1374.︎
  55. Hosseinian SZ, Haghighatdoost F, Hajihashemi P, et al. Effects of gluten on dyspeptic symptoms: a systematic review and meta-analysis of clinical trials. Nutr Rev. 2023 Dec 11;82(1):9-33.
  56. DI Pierro F, Agnelli G, Conti DM, et al. Psychological distress trend in non-celiac gluten sensitivity: is there a role for a gliadin-degrading probiotic strain? Minerva Gastroenterol (Torino). 2023; 69(4):572-574.
  57. Ghalichi F, Ghaemmaghami J, Malek A, et al. Effect of gluten free diet on gastrointestinal and behavioral indices for children with autism spectrum disorders: a randomized clinical trial. World J Pediatr. 2016; 12(4):436-442︎.
  58. Alamri ES. Efficacy of gluten- and casein-free diets on autism spectrum disorders in children. Saudi Med J. 2020 Oct;41(10):1041-1046.
  59. Osowiecka K, Myszkowska-Ryciak J. The Influence of Nutritional Intervention in the Treatment of Hashimoto’s Thyroiditis-A Systematic Review. Nutrients. 2023 Feb 20;15(4):1041.
  60. Guagnano MT, D’Angelo C, Caniglia D, et al. Improvement of Inflammation and Pain after Three Months’ Exclusion Diet in Rheumatoid Arthritis Patients. Nutrients. 2021 Oct 9;13(10):3535.
  61. Lidón AC, Patricia ML, Vinesh D, et al. Evaluation of Gluten Exclusion for the Improvement of Rheumatoid Arthritis in Adults. Nutrients. 2022 Dec 19;14(24):5396.
  62. Almirall M, Casellas F, Dot J, et al. Prevalence of non-coeliac gluten sensitivity and assessment of the response to gluten-free diet in a cohort of patients with fibromyalgia. Rheumatology (Oxford). 2023 Mar 1;62(3):1069-1077.
  63. Passali M, Josefsen K, Frederiksen JL, et al. Current Evidence on the Efficacy of Gluten-Free Diets in Multiple Sclerosis, Psoriasis, Type 1 Diabetes and Autoimmune Thyroid Diseases. Nutrients. 2020 Aug 1;12(8):2316.
  64. Di Lazzaro V, Capone F, Cammarota G, et al. Dramatic improvement of parkinsonian symptoms after gluten-free diet introduction in a patient with silent celiac disease. J Neurol. 2014 Feb;261(2):443-5.
  65. Verdelli A, Corrà A, Mariotti EB, et al. Skin gluten-related disorders: new and old cutaneous manifestations to be considered. Front Med (Lausanne). 2023; 10:1155288.
  66. Weaver KN, Herfarth H. Gluten-Free Diet in IBD: Time for a Recommendation? Mol Nutr Food Res. 2021 Mar;65(5):e1901274.
  67. Bruni O, Dosi C, Luchetti A, et al. An unusual case of drug-resistant epilepsy in a child with non-celiac gluten sensitivity. Seizure. 2014 Sep;23(8):674-6.︎
  68. Selmi O, Khalid B, Al-Nuaimi S. Effects of a Gluten-Free Diet in a Teenager Presenting With Psychosis. Cureus. 2023 Jul 13;15(7):e41807.
  69. Eaton WW, Chen LY, Dohan FC Jr, et al. Improvement in psychotic symptoms after a gluten-free diet in a boy with complex autoimmune illness. Am J Psychiatry. 2015 Mar 1;172(3):219-21.

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