Voedingsgeneeskunde

Zeisel SH, A brief history of choline.Ann Nutr Metab, 2012;61(3):254-8.

Buchman AL. Choline deficiency causes reversible hepatic abnormalities in patients receiving parenteral nutrition: proof of a human choline requirement: a placebo-controlled trial. JPEN J Parenter Enteral Nutr. 2001 Sep-Oct;25(5):260-8.

Shronts EP. Essential nature of choline with implications for total parenteral nutrition. J Am Diet Assoc. 1997 Jun;97(6):639-46, 649.

Zeisel SH, The fetal origins of memory: the role of dietary choline in optimal brain development, J Pediatr. 2006 November ; 149(5 Suppl): S131-S136.

Zeisel SH. Choline: needed for normal development of memory, J Am Coll Nutr 2000; 19(5):528S-531S.

Hollenbeck CB, An introduction to the nutrition and metabolism of choline. Centr Nerv Syst Ag Med Chem 2012; 12:100-113.

Li Z, Vance DE. Phosphatidylcholine and choline homeostasis, J Lipid Res 2008; 49.

Cordero P, Campion J, Milagro FI, Martinez JA. Transcriptomic and epigenetic changes in early liver steatosis associated to obesity: Effect of dietary methyl donor supplementation. Mol Genet Metab. 2013 Nov; 110(3):388-95.

de Wit NJ, Afman LA, Mensink M, Müller M. Phenotyping the effect of diet on non-alcoholic fatty liver disease. J Hepatol. 2012 Dec;57(6):1370-3.

Corbin KD, Zeisel SH, Choline metabolism provides novel insights into non-alcoholic fatty liver disease and its progression, Curr Opin Gastroenterol. 2012 March ; 28(2): 159-165.

Cordero P, Gomez-Uriz AM, Campion J, Milagro FI, Martinez JA. Dietary supplementation with methyl donors reduces fatty liver and modifies the fatty acid synthase DNA methylation profile in rats fed an obesogenic diet. Genes Nutr. 2013 Jan;8(1):105-13.

Jorgacevic B et al. Dynamics of oxidative/nitrosative stress in mice with methionine-choline-deficient diet-induced nonalcoholic fatty liver disease. Hum Exp Toxicol. 2013 Oct 15. [Epub ahead of print]

Mouzaki M, Allard JP. The role of nutrients in the development, progression, and treatment of nonalcoholic fatty liver disease. J Clin Gastroenterol. 2012 Jul;46(6):457-67.

Chiuve SE et al. The association between betaine and choline intakes and the plasma concentrations of homocysteine in women. Am J Clin Nutr. 2007 Oct;86(4):1073-81.

Rajaie S, Esmaillzadeh A, Dietary choline and betaine intakes and risk of cardiovascular diseases: review of epidemiological evidence, ARY Atherosclerosis 2011; 7(2):78-86.

Zhang CX et al. Choline and betaine intake is inversely associated with breast cancer risk: a two-stage case-control study in China. Cancer Sci. 2013 Feb;104(2):250-8.

Ying J, Rahbar MH, Hallman DM, Hernandez LM, Spitz MR, Forman MR, Gorlova OY. Associations between dietary intake of choline and betaine and lung cancer risk. PLoS One. 2013;8(2):e54561.

Innis SM, Davidson AG, Melynk S, James S, Choline-related supplements improve abnormal plasma methioninehomocysteine metabolites and glutathione status in children with cystic fibrosis, Am J Clin Nutr, 2007 Mar;85(3):702-8.

Nurk E et al. Plasma free choline, betaine and cognitive performance: the Hordaland Health Study. Br J Nutr. 2012 May 1:1-9. [Epub ahead of print]

There were significant interactions between low choline or betaine and low vitamin B12 or high MMA on cognitive performance.

Buchman AL et al. Verbal and visual memory improve after choline supplementation in long-term total parenteral nutrition: a pilot study. JPEN J Parenter Enteral Nutr. 2001 Jan-Feb;25(1):30-5.

Mineur YS et al. Cholinergic signaling in the hippocampus regulates social stress resilience and anxiety- and depression-like behavior. Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3573-8.

Bjelland I, Tell GS, Vollset SE, Konstantinova S, Ueland PM. Choline in anxiety and depression: the Hordaland Health Study. Am J Clin Nutr. 2009 Oct;90(4):1056-60.

Gaudin M, Panchal M, Auzeil N, Duyckaerrts C, Brunelle A, Laprévote O, Touboul D, Choline-containing phospholipids in microdissected human Alzheimer’s disease brain senile plaque versus neuropil. Bioanalysis 2012 Sep;4(17):2153-5159.

Gutiérrez-Fernández M et al. CDP-choline treatment induces brain plasticity markers expression in experimental animal stroke. Neurochem Int. 2012 Feb;60(3):310-7.

Gutiérrez-Fernández M et al. CDP-choline at high doses is as effective as i.v. thrombolysis in experimental animal stroke. Neurol Res. 2012 Sep;34(7):649-56.

Secades JJ, Lorenzo JL. Citicoline: pharmacological and clinical review, 2006 update. Methods Find Exp Clin Pharmacol. 2006 Sep;28 Suppl B:1-56.

Fioravanti M, Yanagi M. Cytidinediphosphocholine (CDP-choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly. Cochrane Database Syst Rev. 2005 Apr 18;(2):CD000269.

Hurtado O et al. A chronic treatment with CDP-choline improves functional recovery and increases neuronal plasticity after experimental stroke. Neurobiol Dis. 2007 Apr;26(1):105-11.

Clark WM. Efficacy of citicoline as an acute stroke treatment. Expert Opin Pharmacother. 2009 Apr;10(5):839-46.

Alvarez XA et al. Double-blind placebo-controlled study with citicoline in APOE genotyped Alzheimer's disease patients. Effects on cognitive performance, brain bioelectrical activity and cerebral perfusion. Methods Find Exp Clin Pharmacol. 1999 Nov;21(9):633-44.

Secades JJ, Frontera G. CDP-choline: pharmacological and clinical review. Methods Find Exp Clin Pharmacol. 1995 Oct;17 Suppl B:1-54.

Fagone P, Jackowski S. Phosphatidylcholine and the CDP-choline cycle. Biochim Biophys Acta. 2013 Mar;1831(3):523-32.

Adibhatla RM et al. CDP-choline significantly restores phosphatidylcholine levels by differentially affecting phospholipase A2 and CTP: phosphocholine cytidylyltransferase after stroke. J Biol Chem. 2006 Mar 10;281(10):6718-25.

Zweifler RM. Membrane stabilizer: citicoline. Curr Med Res Opin. 2002;18 Suppl 2:s14-7.

Bagdas D et al. The antihyperalgesic effect of cytidine-5'-diphosphate-choline in neuropathic and inflammatory pain models. Behav Pharmacol. 2011 Sep;22(5-6):589-98.

CDP-choline has antihypersensitivity and antiinflammatory effects

Hurtado O et al. Citicoline (CDP-choline) increases Sirtuin1 expression concomitant to neuroprotection in experimental stroke. J Neurochem. 2013 Sep;126(6):819-26.

Gurun MS, Parker R, Eisenach JC, Vincler M. The effect of peripherally administered CDP-choline in an acute inflammatory pain model: the role of alpha7 nicotinic acetylcholine receptor. Anesth Analg. 2009 May;108(5):1680-7.

Lee SE. Choline, an alpha7 nicotinic acetylcholine receptor agonist, alleviates hyperalgesia in a rat osteoarthritis model. Neurosci Lett. 2013 Aug 26;548:291-5.

Alvarez XA et al. Double-blind placebo-controlled study with citicoline in APOE genotyped Alzheimer's disease patients. Effects on cognitive performance, brain bioelectrical activity and cerebral perfusion. Methods Find Exp Clin Pharmacol. 1999 Nov;21(9):633-44.

Nyakas C, Granic I, Halmy LG, Banerjee P, Luiten PG. The basal forebrain cholinergic system in aging and dementia. Rescuing cholinergic neurons from neurotoxic amyloid-β42 with memantine. Behav Brain Res. 2011 Aug 10;221(2):594-603.

Schliebs R, Arendt T. The cholinergic system in aging and neuronal degeneration. Behav Brain Res. 2011 Aug 10;221(2):555-63.

Cline BN et al. The neuronal insulin sensitizer dicholine succinate reduces stress-induced depressive traits and memory deficit: possible role of insulin-like growth factor 2. BMC Neurosci. 2012 Sep 18;13:110.

Noetzel MJ, Jones CK, Conn PJ. Emerging approaches for treatment of schizophrenia: modulation of glutamatergic signaling. Discov Med. 2012 Nov;14(78):335-43.

Lane HY et al. Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled study. Arch Gen Psychiatry. 2005 Nov;62(11):1196-204.

Brown RP, Gerbarg PL. Herbs and nutrients in the treatment of depression, anxiety, insomnia, migraine, and obesity. J Psychiatr Pract. 2001 Mar;7(2):75-91.

Varela-Moreiras G, Ragel C, Pérez de Miguelsanz J. Choline deficiency and methotrexate treatment induces marked but reversible changes in hepatic folate concentrations, serum homocysteine and DNA methylation rates in rats. J Am Coll Nutr. 1995 Oct;14(5):480-5.

Alonso-Aperte E, Varela-Moreiras G. Brain folates and DNA methylation in rats fed a choline deficient diet or treated with low doses of methotrexate. Int J Vitam Nutr Res. 1996;66(3):232-6.

Lerner V, Antioxidants as a Treatment and Prevention of Tardive Dyskinesia, Handbook of Schizophrenia Spectrum Disorders, Volume III, pp. 109-34.

Zeisel SH. Choline: critical role during fetal development and dietary requirements in adults. Annu Rev Nutr. 2006;26:229-50.

Blusztajn JK, Mellott TJ. Neuroprotective actions of perinatal choline nutrition. Clin Chem Lab Med. 2013 Mar 1;51(3):591-9.

Zeisel SH, Niculescu MD. Perinatal choline influences brain structure and function. Nutr Rev. 2006 Apr;64(4):197-203.

Poly C et al. The relation of dietary choline to cognitive performance and white-matter hyperintensity in the Framingham offspring cohort, Am. J. Clin. Nutr. 2011, 94, 1584-91.

Zeisel SH. Choline: needed for normal development of memory. J Am Coll Nutr. 2000 Oct;19(5 Suppl):528S-531S.

Zeisel SH, Niculescu MD, Perinatal choline influences brain structure and function, Nutr. Rev. 2006 April ; 64(4): 197-203.

Zeisel SH. Nutrition in pregnancy: the argument for including a source of choline. Int J Womens Health. 2013 Apr 22;5:193-9.

Zeisel SH. Nutritional importance of choline for brain development, J Am Coll Nutr 2004; 23(6): 621S-626S

Wainwright PE et al. Postnatal dietary supplementation with either gangliosides or choline: effects on spatial short-term memory in artificially-reared rats. Nutr Neurosci. 2007 Feb-Apr;10(1-2):67-77.

Mehedint MG, Zeisel SH, Choline’s role in maintaining liver function: new evidence for epigenetic mechanisms. Curr Opin Clin Nutr Metab Care, 2013 May; 16(3):339-45.

Allen LH, B-vitamins in breast milk: relative importance of maternal status and intake, and effects on infant status and function, American Society for Nutrition, Adv. Nutr. 3: 362-369, 2012.

Blusztajn JK, Mellott TJ. Choline nutrition programs brain development via DNA and histone methylation. Cent Nerv Syst Agents Med Chem. 2012 Jun;12(2):82-94.

Mehedint MG, Niculescu MD, Craciunescu CN, Zeisel SH. Choline deficiency alters global histone methylation and epigenetic marking at the Re1 site of the calbindin 1 gene. FASEB J. 2010 Jan;24(1):184-95.

Davison JM, Mellott TJ, Kovacheva VP, Blusztajn JK. Gestational choline supply regulates methylation of histone H3, expression of histone methyltransferases G9a (Kmt1c) and Suv39h1 (Kmt1a), and DNA methylation of their genes in rat fetal liver and brain. J Biol Chem. 2009 Jan 23;284(4):1982-9.

Jiang X, Caudill MA et al. Maternal choline intake alters the epigenetic state of fetal cortisol-regulating genes in humans. FASEB J. 2012 Aug;26(8):3563-74.

maternal choline intake in humans modulates the epigenetic state of genes that regulate fetal HPA axis reactivity as well as the epigenomic status of fetal derived tissues.

Wilkinson J. High maternal choline intake may prevent the development of stress-related disorders through epigenetic mechanisms, Epigenomics 10/2012; 4(5) 479-80.

Glenn MJ, Adams RS, McClurg L. Supplemental dietary choline during development exerts antidepressant-like effects in adult female rats. Brain Res. 2012 Mar 14;1443:52-63.

Stene LC, Ulriksen J, Magnus P, Joner G. Use of cod liver oil during pregnancy associated with lower risk of Type I diabetes in the offspring. Diabetologia. 2000 Sep;43(9):1093-8.

Norwegian Childhood Diabetes Study Group. Use of cod liver oil during the first year of life is associated with lower risk of childhood-onset type 1 diabetes: a large, population-based, case-control study. Am J Clin Nutr. 2003 Dec;78(6):1128-34.

Eliades M et al. Meta-analysis: vitamin D and non-alcoholic fatty liver disease. Aliment Pharmacol Ther. 2013 Aug;38(3):246-54.

Targher G, Scorletti E, Mantovani A, Byrne CD. Nonalcoholic fatty liver disease and reduced serum vitamin D(3) levels. Metab Syndr Relat Disord. 2013 Aug;11(4):217-28.

Kwok RM, Torres DM, Harrison SA. Vitamin D and nonalcoholic fatty liver disease (NAFLD): is it more than just an association? Hepatology. 2013 Sep;58(3):1166-74.

Rhee EJ et al. High serum vitamin D levels reduce the risk for nonalcoholic fatty liver disease in healthy men independent of metabolic syndrome. Endocr J. 2013;60(6):743-52.

Roth CL et al. Vitamin D deficiency in obese rats exacerbates nonalcoholic fatty liver disease and increases hepatic resistin and Toll-like receptor activation. Hepatology. 2012 Apr;55(4):1103-11.

Raeder MB, Steen VM, Vollset SE, Bjelland I. Associations between cod liver oil use and symptoms of depression: the Hordaland Health Study. J Affect Disord. 2007 Aug;101(1-3):245-9.

Zeisel SH. Choline: clinical nutrigenetic/nutrigenomic approaches for identification of functions and dietary requirements, J Nutrigenet Nutrogenomics 2010;3:209-219.

Zeisel SH. Gene response elements, genetic polymorphisms and epigenetics influence the human dietary requirement for choline. IUBMB Life. 2007 Jun;59(6):380-7.

Schultz A, Neil D, Aguila MB, Mandarim-de-Lacerda CA. Hepatic adverse effects of fructose consumption independent of overweight/obesity. Int J Mol Sci. 2013 Nov 5;14(11):21873-86.

Vos MB, Lavine JE. Dietary fructose in nonalcoholic fatty liver disease. Hepatology. 2013 Jun;57(6):2525-31.

Ueland PM. Choline and betaine in health and disease, J Inherit Metab Dis (2011) 34:3-15.

Ying J, Gorlova OY et al. Associations between dietary intake of choline and betaine and lung cancer risk. PLoS One. 2013;8(2):e54561.