Vermoeide benen
Problemen met arteriën of venen

Vermoeide en/of pijnlijke benen zijn een typische ouderdomskwaal. De kwaal vermindert autonomie en levenskwaliteit van de lijder, hij of zij is minder in staat zelfstandig huishoudelijke of andersoortige taken uit te voeren. Meestal vallen de klachten onder twee veel voorkomende aandoeningen: perifeer arterieel vaatlijden of veneuze insufficiëntie. Bij de eerste aandoening is er een probleem met de bloedtoevoer naar de benen, bij de tweede is er een probleem met het terugpompen van het bloed. In dit artikel tasten we af in hoeverre voeding en leefstijl vermoeidheid in de benen kan helpen verlichten.

Beste bezoeker, u heeft geen toegang.

Enkel (web)abonnees hebben toegang tot tijdschriftartikelen. Het webabonnement is nog in de maak.

U kunt zich wel alvast (gratis) registreren en tal van andere webartikelen raadplegen!

Auteur

Joost Meeusen

Trefwoorden:

Verschenen in

Referenties

  1. Zemaitis MR, Boll JM, Dreyer MA. Peripheral Arterial Disease. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020

  2. Patel SK, Surowiec SM. Intermittent Claudication. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2020.

  3. Hossain P, Kokkinidis DG, Armstrong EJ. How To Assess a Claudication and When To Intervene. Curr Cardiol Rep. 2019; 21(12):138 doi:10.1007/s11886-019-1227-4

  4. Peach G, Griffin M, Jones KG, Thompson MM, Hinchliffe RJ. Diagnosis and management of peripheral arterial disease. BMJ. 2012;345:e5208. Published 2012 Aug 14. doi:10.1136/bmj.e5208

  5. Lane R, Harwood A, Watson L, Leng GC. Exercise for intermittent claudication. Cochrane Database Syst Rev. 2017 Dec 26;12:CD000990. doi: 10.1002/14651858.CD000990.pub4.

  6. Hageman D, Fokkenrood HJ, Gommans LN et al. Supervised exercise therapy versus home-based exercise therapy versus walking advice for intermittent claudication. Cochrane Database Syst Rev. 2018 Apr 6;4:CD005263. doi: 10.1002/14651858.CD005263.pub4.

  7. Machado I, Sousa N, Paredes H et al. Combined Aerobic and Resistance Exercise in Walking Performance of Patients With Intermittent Claudication: Systematic Review. Front Physiol. 2019; 10:1538 doi:10.3389/fphys.2019.01538

  8. Grenon SM, Cohen BE, Smolderen K et al. Peripheral arterial disease, gender, and depression in the Heart and Soul Study. J Vasc Surg. 2014; 60(2):396-403 doi:10.1016/j.jvs.2014.02.013

  9. Yuyun MF, Ng LL, Ng GA. Endothelial dysfunction, endothelial nitric oxide bioavailability, tetrahydrobiopterin, and 5-methyltetrahydrofolate in cardiovascular disease. Where are we with therapy? Microvasc Res. 2018; 119:7-12 doi:10.1016/j.mvr.2018.03.012

  10. Meeusen J. Levensnoodzakelijke interacties tussen stikstofmonoxide en endotheel. Rol van voeding en voedingssupplementen op NO. Arts, therapeut & apotheker. 2014: 15(2)

  11. Yuyun MF, Ng LL, Ng GA. Endothelial dysfunction, endothelial nitric oxide bioavailability, tetrahydrobiopterin, and 5-methyltetrahydrofolate in cardiovascular disease. Where are we with therapy? Microvasc Res. 2018 Sep;119:7-12. doi: 10.1016/j.mvr.2018.03.012. Epub 2018 Mar 27.

  12. Hoang HH, Padgham SV, Meininger CJ. L-arginine, tetrahydrobiopterin, nitric oxide and diabetes. Curr Opin Clin Nutr Metab Care. 2013; 16(1):76-82 doi:10.1097/MCO.0b013e32835ad1ef

  13. Khandanpour N, Armon MP, Jennings B et al. Randomized clinical trial of folate supplementation in patients with peripheral arterial disease. Br J Surg. 2009; 96(9):990-8 doi:10.1002/bjs.6670

  14. Miller SJ, Unthank JL. Understanding the role of antioxidant therapy for intermittent claudication; good, bad, or both?. Am J Physiol Heart Circ Physiol. 2015;309(5):H734–H736. doi:10.1152/ajpheart.00518.2015

  15. da Silva ND, Roseguini BT, Chehuen M et al. Effects of oral N-acetylcysteine on walking capacity, leg reactive hyperemia, and inflammatory and angiogenic mediators in patients with intermittent claudication. Am J Physiol Heart Circ Physiol. 2015; 309(5):H897-905 doi:10.1152/ajpheart.00158.2015

  16. Langlois M, Duprez D, Delanghe J et al. Serum vitamin C concentration is low in peripheral arterial disease and is associated with inflammation and severity of atherosclerosis. Circulation. 2001; 103(14):1863-8 doi:10.1161/01.cir.103.14.1863

  17. Silvestro A, Scopacasa F, Oliva G et al. Vitamin C prevents endothelial dysfunction induced by acute exercise in patients with intermittent claudication. Atherosclerosis. 2002; 165(2):277-83 doi:10.1016/s0021-9150(02)00235-6

  1. 18.Campbell A, Price J, Hiatt WR. Omega-3 fatty acids for intermittent claudication. Cochrane Database Syst Rev. 2013;(7):CD003833. Published 2013 Jul 4. doi:10.1002/14651858.CD003833.pub4

  1. Ramirez JL, Zahner GJ, Spaulding KA et al. Peripheral Artery Disease Is Associated with a Deficiency of Erythrocyte Membrane n-3 Polyunsaturated Fatty Acids. Lipids. 2019 Apr;54(4):211-219. doi: 10.1002/lipd.12140. Epub 2019 Mar 18.

  2. Lasota AN, Grønholdt MM, Bork CS et al. Marine n-3 Fatty Acids and the Risk of Peripheral Arterial Disease. J Am Coll Cardiol. 2018 Oct 2;72(14):1576-1584. doi: 10.1016/j.jacc.2018.07.045.

  3. De Caterina R, Madonna R. Marine n-3 Fatty Acids and Vascular Disease: Solid Evidence in a Sea of Uncertainties. J Am Coll Cardiol. 2018; 72(14):1585-1588 doi:10.1016/j.jacc.2018.07.044

  4. Madden J, Brunner A, Dastur ND et al. Fish oil induced increase in walking distance, but not ankle brachial pressure index, in peripheral arterial disease is dependent on both body mass index and inflammatory genotype. Prostaglandins Leukot Essent Fatty Acids. 2007 Jun;76(6):331-40. Epub 2007 Jun 27.

  5. Critical Leg Ischaemia Prevention Study (CLIPS) Group, Catalano M, Born G, Peto R et al. Prevention of serious vascular events by aspirin amongst patients with peripheral arterial disease: randomized, double-blind trial. J Intern Med. 2007 Mar;261(3):276-84.

  6. Lane JS, Magno CP, Lane KT et al. Nutrition impacts the prevalence of peripheral arterial disease in the United States. J Vasc Surg. 2008 Oct;48(4):897-904. doi: 10.1016/j.jvs.2008.05.014. Epub 2008 Jun 30.

  7. Gardner AW, Montgomery PS, Wang M et al. Diet is associated with ankle-brachial index, inflammation, and ambulation in patients with intermittent claudication. J Vasc Surg. 2020 Feb 28. pii: S0741-5214(20)30146-4. doi: 10.1016/j.jvs.2019.12.038. [Epub ahead of print]

  8. Heffron SP, Rockman CB, Adelman MA et al. Greater Frequency of Fruit and Vegetable Consumption Is Associated With Lower Prevalence of Peripheral Artery Disease. Arterioscler Thromb Vasc Biol. 2017 Jun;37(6):1234-1240. doi: 10.1161/ATVBAHA.116.308474. Epub 2017 May 18.

  9. Heffron SP, Rockman CB, Gianos E et al. Greater frequency of nut consumption is associated with lower prevalence of peripheral arterial disease. Prev Med. 2015 Mar;72:15-8. doi: 10.1016/j.ypmed.2014.12.014. Epub 2014 Dec 19.

  10. Ruiz-Canela M, Martínez-González MA. Lifestyle and dietary risk factors for peripheral artery disease. Circ J. 2014;78(3):553-9. Epub 2014 Feb 1.

  11. Nicolaï SP, Kruidenier LM, Bendermacher BL et al. Ginkgo biloba for intermittent claudication. Cochrane Database Syst Rev. 2013(6):CD006888 doi:10.1002/14651858.CD006888.pub3

  12. Stewart M, Morling JR, Maxwell H. Padma 28 for intermittent claudication. Cochrane Database Syst Rev. 2016; 3:CD007371 doi:10.1002/14651858.CD007371.pub3

  13. Tenore GC, D'Avino M, Caruso D et al. Effect of Annurca Apple Polyphenols on Intermittent Claudication in Patients With Peripheral Artery Disease. Am J Cardiol. 2019; 123(5):847-853 doi:10.1016/j.amjcard.2018.11.034

  14. McDermott MM, Criqui MH, Domanchuk K et al. Cocoa to Improve Walking Performance in Older People With Peripheral Artery Disease: The COCOA-PAD Pilot Randomized Clinical Trial. Circ Res. 2020; 126(5):589-599 doi:10.1161/CIRCRESAHA.119.315600

  15. Delaney CL, Spark JI, Thomas J et al. A systematic review to evaluate the effectiveness of carnitine supplementation in improving walking performance among individuals with intermittent claudication. Atherosclerosis. 2013 Jul;229(1):1-9. doi: 10.1016/j.atherosclerosis.2013.03.004. Epub 2013 Mar 15.

  16. Luo T, Li J, Li L, Yang B et al. A study on the efficacy and safety assessment of propionyl-L-carnitine tablets in treatment of intermittent claudication. Thromb Res. 2013 Oct;132(4):427-32. doi: 10.1016/j.thromres.2013.08.005. Epub 2013 Aug 14.

  17. Berti-Hearn L, Elliott B. Chronic venous insufficiency: A review for nurses. Nursing. 2019; 49(12):24-30 doi:10.1097/01.NURSE.0000604688.03299.aa

  18. Patel SK, Surowiec SM. Venous Insufficiency. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2020.

  19. Antani MR, Dattilo JB. Varicose Veins. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2020.

  20. Santler B, Goerge T. Chronic venous insufficiency - a review of pathophysiology, diagnosis, and treatment. J Dtsch Dermatol Ges. 2017;15(5):538–556. doi:10.1111/ddg.13242

  21. Antignani PL, Caliumi C. Medical Treatment of Chronic Venous Insufficiency. Vascular Disease Prevention. 2007; 4:117-124

  22. Dogru-Huzmeli E, Fansa I, Cetisli-Korkmaz N et al. Dancing: More than a therapy for patients with venous insufficiency. Vascular. 2020; 28(2):189-195 doi:10.1177/1708538119893534

  23. Kakkos SK, Nicolaides AN. Efficacy of micronized purified flavonoid fraction (Daflon®) on improving individual symptoms, signs and quality of life in patients with chronic venous disease: a systematic review and meta-analysis of randomized double-blind placebo-controlled trials. Int Angiol. 2018; 37(2):143-154 doi:10.23736/S0392-9590.18.03975-5

  24. Jawien A, Bouskela E, Allaert FA, Nicolaïdes AN. The place of Ruscus extract, hesperidin methyl chalcone, and vitamin C in the management of chronic venous disease. Int Angiol. 2017; 36(1):31-41 doi:10.23736/S0392-9590.16.03788-3

  25. Kakkos SK, Bouskela E, Jawien A, Nicolaides AN. New data on chronic venous disease: a new place for Cyclo 3® Fort. Int Angiol. 2018; 37(1):85-92 doi:10.23736/S0392-9590.17.03935-9

  26. Kakkos SK, Allaert FA. Efficacy of Ruscus extract, HMC and vitamin C, constituents of Cyclo 3 fort®, on improving individual venous symptoms and edema: a systematic review and meta-analysis of randomized double-blind placebo-controlled trials. Int Angiol. 2017; 36(2):93-106 doi:10.23736/S0392-9590.17.03815-9

  27. Gulati OP. Pycnogenol® in chronic venous insufficiency and related venous disorders. Phytother Res. 2014; 28(3):348-62 doi:10.1002/ptr.5019

  28. Cesarone MR, Belcaro G, Rohdewald P, et al. Improvement of signs and symptoms of chronic venous insufficiency and microangiopathy with Pycnogenol: a prospective, controlled study. Phytomedicine. 2010;17(11):835–839. doi:10.1016/j.phymed.2010.04.009

  29. Pittler MH, Ernst E. Horse chestnut seed extract for chronic venous insufficiency. Cochrane Database Syst Rev. 2006(1):CD003230 doi:10.1002/14651858.CD003230.pub3

  30. Gallelli L. Escin: a review of its anti-edematous, anti-inflammatory, and venotonic properties. Drug Des Devel Ther. 2019; 13:3425-3437 doi:10.2147/DDDT.S207720

Gerelateerde artikelen

Het verband tussen leefstijl, voeding en psyche
Ginkgo biloba effectief bij dyslexie
Omega-3 neutraliseert ‘early life stress’
Meer omega-3 in biologische melk
Fietsers hebben geen leeftijd