Ontsteking en beschadiging van de schildklier door een auto-immuunreactie (auto-immuunthyroïditis) is de meest voorkomende (sub)klinische auto-immuunziekte bij de mens en komt naar schatting bij 2-5% van de jodiumsufficiënte bevolking voor.1-3 Auto-immuunthyroïditis leidt meestal tot hypothyroïdie (Hashimoto) en in een beperkt aantal gevallen tot hyperthyroïdie (Graves). Het reguliere antwoord op hypothyroïdie door auto-immuunthyroïditis is substitutietherapie met (synthetisch) schildklierhormoon (L-thyroxine). Een zeer effectieve manier van symptoombestrijding. Helaas wordt voorbijgegaan aan toenemend wetenschappelijk bewijs dat essentiële voedingsstoffen zoals selenium en vitamine D een rol spelen bij de preventie van de ziekte van Hashimoto en vermoedelijk ziekteprogressie remmen.
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