In recente decennia werd enorm veel moeite gedaan om het pathogenetische proces van auto-immuunziekten te ontraadselen. Auto-immuniteit is een ingewikkeld, multifactorieel proces: immunologische, genetische, omgevings-, hormonale én neuropsychologische factoren spelen alle een rol in de ‘auto-immuniteit mozaïek’, waarin je door het bos de bomen niet meer ziet … of omgekeerd!
Er zijn thans al meer dan 80 systemische en orgaanspecifieke auto-immuunziekten gedefinieerd, en de cumulatieve last ervan is substantieel, zowel individueel, medisch als financieel. En er wordt verwacht dat de incidentie ervan enkel zal stijgen.
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