Granaatappels staan bekend om hun natuurlijke polyfenolen. Minder bekend is dat deze polyfenolen voedingsbron zijn voor de darmmicrobiota die deze omzetten in urolithinen, een groep stoffen die in het afgelopen decennium bijzondere aandacht van de wetenschap kreeg. Urolithinen blijken een gunstig effect te hebben op de mitochondriën en kunnen daarmee veroudering afremmen.
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