Voedselspecifieke IgG’s
Getroebleerde biomarkers voor voedselintolerantie

IgG-tests detecteren IgG-antilichamen in het bloed die met een voedselantigeen binden. Vaak detecteren ze honderden antigenen tegelijk. Verkopers beweren dat de test een bewijs is voor voedselintolerantie, maar in reguliere kringen wordt die praktijk resoluut afgewezen. Dit vijfde deel van de reeks artikelen over voedselintoleranties wordt dus een verhaal met vele voors en tegens.

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Auteur

Joost Meeusen

Trefwoorden:

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Referenties

  1. Lavine E. Blood testing for sensitivity, allergy or intolerance to food. CMAJ. 2012 Apr 3;184(6):666-8.
  2. Carr S, Chan E, Lavine E, et al. CSACI Position statement on the testing of food-specific IgG. Allergy Asthma Clin Immunol. 2012 Jul 26;8(1):12.
  3. Gerez IF, Shek LP, Chng HH, et al. Diagnostic tests for food allergy. Singapore Med J. 2010 Jan;51(1):4-9︎.
  4. Hammond C, Lieberman JA. Unproven Diagnostic Tests for Food Allergy. Immunol Allergy Clin North Am. 2018 Feb;38(1):153-163.
  5. Fedor I, Zold E, Barta Z. Food-specific IgG Antibodies in Crohn’s Disease: What Came First, the Chicken or the Egg? Intern Med. 2019; 58(14):2123.
  6. Qin L, Tang LF, Cheng L, et al. The clinical significance of allergen-specific IgG4 in allergic diseases. Front Immunol. 2022; 13:1032909.︎
  7. Vidarsson G, Dekkers G, Rispens T. IgG subclasses and allotypes: from structure to effector functions. Front Immunol. 2014; 5:520.
  8. Clayton F, Fang JC, Gleich GJ, et al. Eosinophilic esophagitis in adults is associated with IgG4 and not mediated by IgE. Gastroenterology. 2014 Sep;147(3):602-9.︎
  9. Finkelman FD, Khodoun MV, Strait R. Human IgE-independent systemic anaphylaxis. J Allergy Clin Immunol. 2016 Jun;137(6):1674-1680.
  10. Wu M, Wang X, Sun L, et al. Associations between food-specific IgG and health outcomes in an asymptomatic physical examination cohort. Nutr Metab (Lond). 2022; 19(1):22.
  11. Pantoja-Arévalo L, Gesteiro E, Matthias T, et al. Association between Food-Specific Immunoglobulin G4 Antibodies in Adults with Self-Reported Signs and Symptoms Attributed to Adverse Reactions to Foodstuffs. Biomedicines. 2023; 11(12).
  12. Bentz S, Hausmann M, Piberger H, et al. Clinical relevance of IgG antibodies against food antigens in Crohn’s disease: a double-blind cross-over diet intervention study. Digestion. 2010; 81(4):252-64.
  13. Wang HY, Li Y, Li JJ, et al. Serological investigation of IgG and IgE antibodies against food antigens in patients with inflammatory bowel disease. World J Clin Cases. 2019; 7(16):2189-2203.
  14. Xiao N, Liu F, Zhou G, et al. Food-specific IgGs Are Highly Increased in the Sera of Patients with Inflammatory Bowel Disease and Are Clinically Relevant to the Pathogenesis. Intern Med. 2018; 57(19):2787-2798.
  15. Piuri G, Ferrazzi E, Speciani AF. Blind Analysis of Food-Related IgG Identifies Five Possible Nutritional Clusters for the Italian Population: Future Implications for Pregnancy and Lactation. Nutrients. 2019; 11(5).
  16. Atkinson W, Sheldon TA, Shaath N, et al. Food elimination based on IgG antibodies in irritable bowel syndrome: a randomised controlled trial. Gut. 2004; 53(10):1459-64︎.
  17. Hunter JO. Food elimination in IBS: the case for IgG testing remains doubtful. Gut. 2005 Aug;54(8):1203; author reply 1203︎.
  18. Sewell WA. IgG food antibodies should be studied in similarly treated groups. Gut. 2005 Apr;54(4):566︎.
  19. Mawdsley JE, Irving P, Makins R. IgG antibodies to foods in IBS. Gut. 2005 Apr;54(4):567︎.
  20. Guo H, Jiang T, Wang J, et al. The value of eliminating foods according to food-specific immunoglobulin G antibodies in irritable bowel syndrome with diarrhoea. J Int Med Res. 2012; 40(1):204-10︎.
  21. Cappelletti M, Tognon E, Vona L, et al. Food-specific serum IgG and symptom reduction with a personalized, unrestricted-calorie diet of six weeks in Irritable Bowel Syndrome (IBS). Nutr Metab (Lond). 2020; 17(1):101.
  22. Ostrowska L, Wasiluk D, Lieners CFJ, et al. Igg Food Antibody Guided Elimination-Rotation Diet Was More Effective than FODMAP Diet and Control Diet in the Treatment of Women with Mixed IBS-Results from an Open Label Study. J Clin Med. 2021; 10(19).
  23. Jian L, Anqi H, Gang L, et al. Food Exclusion Based on IgG Antibodies Alleviates Symptoms in Ulcerative Colitis: A Prospective Study. Inflamm Bowel Dis. 2018; 24(9):1918-1925.
  24. Zhao Z, Jin H, Yin Y, et al. Association of Migraine with Its Comorbidities and Food Specific Immunoglobulin G Antibodies and Inflammatory Cytokines: Cross-Sectional Clinical Research. J Pain Res. 2021; 14:2359-2368.
  25. Mitchell N, Hewitt CE, Jayakody S, et al. Randomised controlled trial of food elimination diet based on IgG antibodies for the prevention of migraine like headaches. Nutr J. 2011 Aug 11;10:85.
  26. Xie Y, Zhou G, Xu Y, et al. Effects of Diet Based on IgG Elimination Combined with Probiotics on Migraine Plus Irritable Bowel Syndrome. Pain Res Manag. 2019; 2019:7890461.
  27. Casini I, Fatighenti E, Giannantoni A, et al. Food-Specific IgG4 Antibody-Guided Exclusion Diet Improves Conditions of Patients with Chronic Pain. Pain Ther. 2022 Sep;11(3):873-906.
  28. Wright BL, Kulis M, Guo R, et al. Food-specific IgG4 is associated with eosinophilic esophagitis. J Allergy Clin Immunol. 2016; 138(4):1190-1192.e3.
  29. Lim AHW, Ngoi B, Perkins GB, et al. Outcomes of Serum Food-Specific Immunoglobulin G 4 to Guide Elimination Diet in Patients With Eosinophilic Esophagitis. Am J Gastroenterol. 2024; 119(6):1066-1073.
  30. Karakuła-Juchnowicz H, Szachta P, Opolska A, et al. The role of IgG hypersensitivity in the pathogenesis and therapy of depressive disorders. Nutr Neurosci. 2017 Feb;20(2):110-118.
  31. Vita AA, Zwickey H, Bradley R. Associations between food-specific IgG antibodies and intestinal permeability biomarkers. Front Nutr. 2022; 9:962093.
  32. Pascual J, Oterino A. IgG-mediated allergy: a new mechanism for migraine attacks? Cephalalgia. 2010; 30(7):777-9.
  33. Stöver A, Haberl B, Helmreich C, et al. Fatal Immunohaemolysis after the Consumption of the Poison Pax Mushroom: A Focus on the Diagnosis of the Paxillus Syndrome with the Aid of Two Case Reports. Diagnostics (Basel). 2019 Sep 26;9(4):130.︎

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