Vroegtijdige veroudering, neurodegeneratie, cognitieve achteruitgang en aandoeningen zoals overgewicht, hart- en vaatziekten en diabetes type 2 worden steeds vaker geassocieerd met verstoringen in mitochondriale functie, celcyclus, DNA-herstel en in het immuunsysteem. Bij al deze processen is NAD+ betrokken.
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