Polyfenolen als prebiotica
De gezondheidseffecten van polyfenolen gaan via de darm

Polyfenolen beïnvloeden de samenstelling van de darmmicrobiota en indien ze dat op een gunstige manier doen, mogen we ze prebiotica noemen (of misschien ‘fytobiotica’). Wetenschappers breken nu het hoofd over welk werkingsmechanisme het belangrijkst is: de rechtstreekse bioactiviteit van polyfenolen in het lichaam of de prebiotische activiteit. Zeker is dat de darmmicrobiota essentieel is voor de aanmaak van metabolieten uit polyfenolen, die beter opneembaar zijn dan de oorspronkelijke polyfenolen. Ellagitanninen wordt vaak als model gebruikt.

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Auteur

Joost Meeusen

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Referenties

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