In de VS lijdt 30 % aan een of andere vorm van artritis, 20 %
heeft hiervoor medicatie nodig en 5 - 10 % voelt zich hierdoor geïnvalideerd. Het risico dat iemand artrose oploopt tijdens zijn/haar leven is ongeveer 44 %;
radiologisch onderzoek suggereert dat virtueel elke 60-plusser tekenen van artrose heeft (maar niet de symptomen). Voor wie deze cijfers nog niet schokkend genoeg zijn: tegen artrose bestaat geen goede medicatie, al is voor reuma de toestand beter. Vele patiënten nemen daarom hun toevlucht naar niet-conventionele therapieën. Dit artikel is een overzicht van nutritionele en fytotherapeutische remedies waarrond in de laatste decennia formeel onderzoek is gevoerd.
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Referenties
- Leventhal LJ, Boyce EG et al. Treatment of rheumatoid arthritis with blackcurrant seed oil. Br J Rheumatol. 1994 Sep;33(9):847-52
- Bhattacharya I, Saxena R, Gupta V. Efficacy of vitamin E in knee osteoarthritis management of North Indian geriatric population. Ther Adv Musculoskelet Dis. 2012 Feb;4(1):11-9
-
Canter PH, Wider B et al. The antioxidant vitamins A, C, E and selenium in the treatment of arthritis: a systematic review of randomized clinical trials. Rheumatology (Oxford).
2007 Aug;46(8):1223-33 -
Deal C.
Bone loss in rheumatoid arthritis: systemic, periarticular, and focal. Curr Rheumatol Rep. 2012
Jun;14(3):231-7 - Frei B, Birlouez-Aragon I et al. Authors' perspective: What is the optimum intake of vitamin C in humans? Crit Rev Food Sci Nutr. 2012;52(9):815-29
- Hertz Jensen N. [Reduced pain from osteoarthritis in hip joint or knee joint during treatment with calcium ascorbate. A randomized, placebo-controlled cross-over trial in general practice]. Ugeskr Laeger 2003;165:2563-6
-
Hurley MV. The role of muscle weakness in the pathogenesis of osteoarthritis. Rheum Dis Clin North Am.
1999 May;25(2):283-98, vi. -
Kjeldsen-Kragh J, Haugen M et al. Controlled trial of fasting and one-year vegetarian diet in rheumatoid arthritis.
Lancet. 1991 Oct 12;338(8772):899-902 -
Kjeldsen-Kragh J.
Mediterranean diet intervention in rheumatoid arthritis. Ann Rheum Dis. 2003 Mar;62(3):193-5 -
König B. A long-term (two years) clinical trial with S-adenosylmethionine for the treatment of osteoarthritis. Am J
Med. 1987 Nov 20;83(5A):89-94 -
Lee YH, Woo JH et al. Effect of glucosamine or chondroitin sulfate on the osteoarthritis progression: a meta-analysis. Rheumatol Int. 2010
Jan;30(3):357-63 - McAlindon TE, Jacques P et al. Do antioxidant micronutrients protect against the development and progression of knee osteoarthritis? Arthritis Rheum. 1996 Apr;39(4):648-56
-
Prado CM, Wells JC et al. Sarcopenic obesity: A Critical appraisal of the current evidence. Clin Nutr. 2012
Oct;31(5):583-601 - Roos EM, Herzog W et al. Muscle weakness, afferent sensory dysfunction and exercise in knee osteoarthritis. Nat Rev Rheumatol. 2011 Jan;7(1):57-63
- Rutjes AW, Nüesch E et al. S-Adenosylmethionine for osteoarthritis of the knee or hip. Cochrane Database Syst Rev. 2009 Oct 7;(4):CD007321
-
Schneider H, Maheu E et al. Symptom-modifying effect of chondroitin sulfate in knee osteoarthritis: a meta-analysis of randomized placebo-controlled trials performed with structum(®).
Open Rheumatol J. 2012;6:183-9 -
Shakoor N, Furmanov S et al. Pain and its relationship with muscle strength and proprioception in knee OA: results of an 8-week home exercise pilot study. J
Musculoskelet Neuronal Interact. 2008 Jan-Mar;8(1):35-42 -
Smedslund G, Byfuglien MG et al. Effectiveness and safety of dietary interventions for rheumatoid arthritis: a systematic review of randomized controlled trials. J
Am Diet Assoc. 2010 May;110(5):727-35 -
Volpi N.
Quality of different chondroitin sulfate preparations in relation to their therapeutic activity. J Pharm Pharmacol. 2009 Oct;61(10):1271-80 - Zurier RB, Rossetti RG et al. Gamma-Linolenic acid treatment of rheumatoid arthritis. A randomized, placebo-controlled trial. Arthritis Rheum. 1996 Nov;39(11):1808-17
- Leventhal LJ, Boyce EG et al. Treatment of rheumatoid arthritis with gammalinolenic acid. Ann Intern Med. 1993 Nov 1;119(9):867-73
- Wu YJ, Lao ZY, Zhang ZL. [Clinical observation on small doses Tripterygium wilfordii polyglycoside combined with methotrexate in treating rheumatoid arthritis]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2001 Dec;21(12):895-6
-
Goldbach-Mansky R, Wilson M et al. Comparison of Tripterygium wilfordii Hook F
versus sulfasalazine in the treatment of rheumatoid arthritis: a randomized trial. Ann Intern Med. 2009 Aug 18;151(4):229-40, W49-51. -
Tao X, Younger J et al. Benefit of an extract of Tripterygium Wilfordii Hook F in patients with rheumatoid arthritis: a double-blind, placebo-controlled study. Arthritis Rheum.
2002 Jul;46(7):1735-43 -
Tao X, Cush JJ et al. A phase I study of ethyl acetate extract of the chinese antirheumatic herb Tripterygium wilfordii hook F in rheumatoid arthritis. J
Rheumatol. 2001 Oct;28(10):2160-7 -
Tao XL, Sun Y et al. A prospective, controlled, double-blind, cross-over study of tripterygium wilfodii hook F in treatment of rheumatoid arthritis. Chin Med J (Engl). 1989
May;102(5):327-32 - Cleland LG, James MJ. Osteoarthritis. Omega-3 fatty acids and synovitis in osteoarthritic knees. Nat Rev Rheumatol. 2012 Apr 17;8(6):314-5
-
Lee YH, Bae SC et al.
Omega-3 polyunsaturated fatty acids and the treatment of rheumatoid arthritis: a meta-analysis. Arch Med Res. 2012 Jul;43(5):356-62 -
Sundrarjun T, Komindr S et al. Effects of n-3 fatty acids on serum interleukin-6, tumour necrosis factor-alpha and soluble tumour necrosis factor receptor p55 in active rheumatoid arthritis. J
Int Med Res. 2004 Sep-Oct;32(5):443-54 - Di Giuseppe D, Wallin A et al. Long-term intake of dietary long-chain n-3 polyunsaturated fatty acids and risk of rheumatoid arthritis: a prospective cohort study of women. Ann Rheum Dis. 2013 Aug 12. doi: 10.1136/annrheumdis-2013-203338
-
Rosell M, Wesley AM et al. Dietary fish and fish oil and the risk of rheumatoid arthritis. Epidemiology. 2009
Nov;20(6):896-901 -
Kulkarni RR, Patki PS et al. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J
Ethnopharmacol. 1991 May-Jun;33(1-2):91-5 -
Singh BB, Mishra LC et al. The effectiveness of Commiphora mukul for osteoarthritis of the knee: an outcomes study.
Altern Ther Health Med. 2003
May-Jun;9(3):74-9 -
Drozdov VN, Kim VA et al. Influence of a specific ginger combination on gastropathy conditions in patients with osteoarthritis of the knee or hip. J
Altern Complement Med. 2012 Jun;18(6):583-8 - Niempoog S, Pawa KK. The efficacy of powdered ginger in osteoarthritis of the knee. J Med Assoc Thai. 2012 Jan;95 Suppl 1:S59-64
-
Zahmatkash M, Vafaeenasab MR. Comparing analgesic effects of a topical herbal mixed medicine with salicylate in patients with knee osteoarthritis.
Pak J Biol Sci. 2011 Jul 1;14(13):715-9 - Therkleson T. Ginger compress therapy for adults with osteoarthritis. Adv Nurs. 2010 Oct;66(10):2225-33
- Wigler I, Grotto I et al. The effects of Zintona EC (a ginger extract) on symptomatic gonarthritis. Osteoarthritis Cartilage. 2003 Nov;11(11):783-9
- Altman RD, Marcussen KC. Effects of a ginger extract on knee pain in patients with osteoarthritis. Arthritis Rheum. 2001 Nov;44(11):2531-8
-
Bliddal H, Rosetzsky A et al. A randomized, placebo-controlled, cross-over study of ginger extracts and ibuprofen in osteoarthritis.
Osteoarthritis Cartilage. 2000
Jan;8(1):9-12 -
Chandran B, Goel A. A randomized, pilot study to assess the efficacy and safety of curcumin in patients with active rheumatoid arthritis.
Phytother Res. 2012 Nov;26(11):1719-25 -
Lukaczer D, Darland G, Tripp M, Liska D, Lerman RH, Schiltz B, Bland JS. A
pilot trial evaluating Meta050, a proprietary combination of reduced iso-alpha acids, rosemary extract and oleanolic acid in patients with arthritis and fibromyalgia. Phytother Res. 2005 Oct;19(10):864-9 -
Blake DR, Robson P et al. Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis. Rheumatology (Oxford). 2006
Jan;45(1):50-2 -
Russo EB, Guy GW et al. Cannabis, pain, and sleep: lessons from therapeutic clinical trials of Sativex, a cannabis-based medicine.
Chem Biodivers. 2007 Aug;4(8):1729-43 - Bálint G, Apáthy A et al. Effect of Avemar--a fermented wheat germ extract--on rheumatoid arthritis. Preliminary data. Clin Exp Rheumatol. 2006 May-Jun;24(3):325-8
- Chopra A, Lavin P, Patwardhan B, Chitre D. A 32-week randomized, placebo-controlled clinical evaluation of RA-11, an Ayurvedic drug, on osteoarthritis of the knees. J Clin Rheumatol. 2004 Oct;10(5):236-45
-
Mandel DR, Eichas K et al.
Bacillus coagulans: a viable adjunct therapy for relieving symptoms of rheumatoid arthritis according to a randomized, controlled trial. BMC Complement Altern Med. 2010
Jan 12;10:1 - Pineda Mde L, Thompson SF et al. A randomized, double-blinded, placebo-controlled pilot study of probiotics in active rheumatoid arthritis. Med Sci Monit. 2011 Jun;17(6):CR347-54.
-
De Vos M, Van Praet L et al. Osteoarticular Manifestations: Specific Treatments and/or Treating Intestinal Disease. Dig Dis.
2013;31(2):239-43 - Nozaki K, Hikiami H et al. Keishibukuryogan (gui-zhi-fu-ling-wan), a Kampo formula, decreases disease activity and soluble vascular adhesion molecule-1 in patients with rheumatoid arthritis. Evid Based Complement Alternat Med. 2006 Sep;3(3):359-64
-
Ogawa K, Kojima T et al. Identification of a predictive biomarker for the beneficial effect of a Kampo (Japanese traditional) medicine keishibukuryogan in rheumatoid arthritis patients. Clin Biochem. 2007
Oct;40(15):1113-21 -
Kogure T, Sato H et al. Serum levels of anti-cyclic citrullinated peptide antibodies are associated with a beneficial response to traditional herbal medicine (Kampo) in rheumatoid arthritis. Rheumatol Int. 2009
Oct;29(12):1441-7 -
Crowley DC, Lau FC et al. Safety and efficacy of undenatured type II
collagen in the treatment of osteoarthritis of the knee: a clinical trial. Int J Med Sci. 2009 Oct 9;6(6):312-21 - Cohen A, Goldman J.Bromelains therapy in rheumatoid arthritis. Pa Med J. 1964 Jun;67:27-30
- Christensen R, Bartels EM et al. Does the hip powder of Rosa canina (rosehip) reduce pain in osteoarthritis patients?--a meta-analysis of randomized controlled trials. Osteoarthritis Cartilage. 2008 Sep;16(9):965-72
-
Willich SN, Rossnagel K et al. Rose hip herbal remedy in patients with rheumatoid arthritis - a randomised controlled trial. Phytomedicine. 2010
Feb;17(2):87-93 -
McAlindon T, LaValley M et al. Effect of vitamin D supplementation on progression of knee pain and cartilage volume loss in patients with symptomatic osteoarthritis: a randomized controlled trial. JAMA.
2013 Jan 9;309(2):155-62 -
Towheed TE, Anastassiades T. Glucosamine Therapy for Osteoarthritis: An Update. J Rheumatol. 2007
Sep;34(9):1787-90 -
Belcaro G, Cesarone MR et al.a
Efficacy and safety of Meriva®, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients.
Altern Med Rev. 2010 Dec;15(4):337-44 -
Belcaro G, Cesarone MR et al.b
Product-evaluation registry of Meriva®, a curcumin-phosphatidylcholine complex, for the complementary management of osteoarthritis. Panminerva Med. 2010 Jun;52(2 Suppl 1):55-62 -
Sengupta K, Krishnaraju AV et al. Comparative efficacy and tolerability of 5-Loxin and Aflapin Against osteoarthritis of the knee: a double blind, randomized, placebo controlled clinical study. Int J Med Sci.
2010 Nov 1;7(6):366-77 - Sengupta K, Alluri KV et al. A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin for treatment of osteoarthritis of the knee. Arthritis Res Ther. 2008;10(4):R85
-
Abdel-Tawab M, Werz O et al. Boswellia serrata: an overall assessment of in vitro, preclinical, pharmacokinetic and clinical data. Clin Pharmacokinet. 2011
Jun;50(6):349-69 - Chopra A, Saluja M et al. Ayurvedic medicine offers a good alternative to glucosamine and celecoxib in the treatment of symptomatic knee osteoarthritis: a randomized, double-blind, controlled equivalence drug trial. Rheumatology (Oxford). 2013 Aug;52(8):1408-17
-
Chopra A, Lavin P et al. A 32-week randomized, placebo-controlled clinical evaluation of RA-11, an Ayurvedic drug, on osteoarthritis of the knees. J Clin Rheumatol. 2004
Oct;10(5):236-45. - [anoniem] Boswellia serrata. Monograph. Altern Med Rev. 2008 Jun;13(2):165-7.
- Kimmatkar N, Thawani V et al. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. Phytomedicine. 2003 Jan;10(1):3-7
- Gupta I, Gupta V, Parihar A, Gupta S, Lüdtke R, Safayhi H, Ammon HP. Effects of Boswellia serrata gum resin in patients with bronchial asthma: results of a double-blind, placebo-controlled, 6-week clinical study. Eur J Med Res. 1998 Nov 17;3(11):511-4
-
Bagchi D, Moriyama H et al. Arthritis: Pathophysiology, prevention, and therapeutics. CRC
Press; 1 edition, April 5, 2011 -
Brien S, Prescott P et al. Systematic review of the nutritional supplement Perna Canaliculus (green-lipped mussel) in the treatment of osteoarthritis. QJM. 2008
Mar;101(3):167-79 - Doggrell SA. Lyprinol-is it a useful anti-inflammatory agent? Evid Based Complement Alternat Med. 2011; 2011:307121
-
Hein GE, Köhler M et al.
The advanced glycation end product pentosidine correlates to IL-6 and other relevant inflammatory markers in rheumatoid arthritis. Rheumatol Int. 2005 Dec;26(2):137-41 -
Senolt L, Braun M et al.
Increased pentosidine, an advanced glycation end product, in serum and synovial fluid from patients with knee osteoarthritis and its relation with cartilage oligomeric matrix protein. Ann Rheum Dis. 2005 Jun;64(6):886-90 - Talent JM, Gracy RW. Pilot study of oral polymeric N-acetyl-D-glucosamine as a potential treatment for patients with osteoarthritis. Clin Ther. 1996 Nov-Dec;18(6):1184-90
-
Klein G, Kullich W, Schnitker J, Schwann H. Efficacy and tolerance of an oral enzyme combination in painful osteoarthritis of the hip. A
double-blind, randomised study comparing oral enzymes with non-steroidal anti-inflammatory drugs. Clin Exp Rheumatol.
2006 Jan-Feb;24(1):25-30 - Cobb CS, Ernst E. Systematic review of a marine nutriceutical supplement in clinical trials for arthritis: the effectiveness of the New Zealand green-lipped mussel Perna canaliculus. Clin Rheumatol. 2006 May;25(3):275-84
- Lippiello L, Nardo JV et al. Metabolic effects of avocado/soy unsaponifiables on articular chondrocytes. Evid Based Complement Alternat Med. 2008 Jun;5(2):191-7
-
Adegbehingbe OO, Adesanya SA et al. Clinical effects of Garcinia kola in knee osteoarthritis. J Orthop Surg Res. 2008
Jul 30;3:34 - Jung YB, Roh KJ et al. Effect of SKI 306X, a new herbal anti-arthritic agent, in patients with osteoarthritis of the knee: a double-blind placebo controlled study. Am J Chin Med. 2001;29(3-4):485-91
-
Teekachunhatean S, Kunanusorn P et al. Chinese herbal recipe versus diclofenac in symptomatic treatment of osteoarthritis of the knee: a randomized controlled trial [ISRCTN70292892]. BMC
Complement Altern Med. 2004 Dec 13;4:19 - Maheu E, Cadet C et al. Randomised, controlled trial of avocado-soybean unsaponifiable (Piascledine) effect on structure modification in hip osteoarthritis: the ERADIAS study. Ann Rheum Dis. 2013 Jan 23
-
Ernst E.
Avocado-soybean unsaponifiables (ASU) for osteoarthritis - a systematic review. Clin Rheumatol. 2003 Oct;22(4-5):285-8 -
[anoniem]
Harpagophytum procumbens (devil's claw). Monograph. Altern Med Rev.
2008 Sep;13(3):248-52 - Piscoya J, Rodriguez Z et al. Efficacy and safety of freeze-dried cat's claw in osteoarthritis of the knee: mechanisms of action of the species Uncaria guianensis. Inflamm Res. 2001 Sep;50(9):442-8.
-
Codolo G, Bossi F et al. Orchestration of inflammation and adaptive immunity in Borrelia burgdorferi-induced arthritis by neutrophil-activating protein A. Arthritis Rheum. 2013
May;65(5):1232-42 -
Reichert S, Haffner M et al. Detection of oral bacterial DNA in synovial fluid. J
Clin Periodontol. 2013 Jun;40(6):591-8 - Zhang X, Rimpiläinen M et al. Enzyme degradation and proinflammatory activity in arthritogenic and nonarthritogenic Eubacterium aerofaciens cell walls. Infect Immun. 2001 Dec;69(12):7277-84
- Bjordal JM, Klovning A et al. Short-term efficacy of pharmacotherapeutic interventions in osteoarthritic knee pain: A meta-analysis of randomised placebo-controlled trials. Eur J Pain. 2007 Feb;11(2):125-38
-
Christensen R, Bartels EM et al. Symptomatic efficacy of avocado-soybean unsaponifiables (ASU) in osteoarthritis (OA) patients: a meta-analysis of randomized controlled trials.
Osteoarthritis Cartilage. 2008 Apr;16(4):399-408 - Chopra A, Saluja M et al. Comparable efficacy of standardized Ayurveda formulation and hydroxychloroquine sulfate (HCQS) in the treatment of rheumatoid arthritis (RA): a randomized investigator-blind controlled study. Clin Rheumatol. 2012 Feb;31(2):259-69.
-
Etzel R.
Special extract of BOSWELLIA serrata (H 15) in the treatment of rheumatoid arthritis. Phytomedicine. 1996
May;3(1):91-4 - Gagnier JJ, van Tulder MW, Berman B, Bombardier C. Herbal medicine for low back pain: a Cochrane review. Spine (Phila Pa 1976). 2007 Jan 1;32(1):82-92
- Warnock M, McBean D et al. Effectiveness and safety of Devil's Claw tablets in patients with general rheumatic disorders. Phytother Res. 2007 Dec;21(12):1228-33
-
Mur E, Hartig F et al. Randomized double blind trial of an extract from the pentacyclic alkaloid-chemotype of uncaria tomentosa for the treatment of rheumatoid arthritis. J
Rheumatol. 2002 Apr;29(4):678-81 - Jacquet A, Girodet P-P et al. Phytalgic, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trial. Arthritis Research & Therapy 2009, 11:R192
-
Christensen R, Bliddal H.
Is Phytalgic(R) a goldmine for osteoarthritis patients or is there something fishy about this nutraceutical? A summary of findings and risk-of-bias assessment. Arthritis Res Ther. 2010;12(1):105 - Matsuno H, Nakamura H et al. Effects of an oral administration of glucosamine-chondroitin-quercetin glucoside on the synovial fluid properties in patients with osteoarthritis and rheumatoid arthritis. Biosci Biotechnol Biochem. 2009 Feb;73(2):288-92
- Nakasone Y, Watabe K et al. Effect of a glucosamine-based combination supplement containing chondroitin sulfate and antioxidant micronutrients in subjects with symptomatic knee osteoarthritis: A pilot study. Exp Ther Med. 2011 Sep;2(5):893-899
- Kim LS, Axelrod LJ et al. Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis Cartilage. 2006 Mar;14(3):286-94
-
Debbi EM, Agar G et al. Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study. BMC
Complement Altern Med. 2011 Jun 27;11:50