Vitamine D krijgen we vooral door blootstelling van onze huid aan zonlicht (ongeveer 90%) en voor een kleiner deel uit onze voeding (10%).1-3 Het wordt via 25-hydroxyvitamine D [25(OH)D, de vitamine D-statusmarker] omgezet naar het vitamine D-hormoon [1,25(OH)2D], dat niet alleen werkzaam is ten behoeve van het calcium/fosfaat-metabolisme van onze botten4 en spieren, maar ook talrijke andere functies heeft,5-12 onder andere in ons immuunsysteem.13 Onlangs werd in de pers melding gemaakt van het overlijden van ‘een oudere persoon’ in België aan een overdosis vitamine D. Een hoog-gedoseerd preparaat, bedoeld voor maandelijkse inname, werd abusievelijk dagelijks gebruikt gedurende twee maanden.14-16 Vastgesteld werd een te hoog calcium en vitamine D in het bloed.15
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Vitamine D
1. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease_Holick AJCN 2004
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https://pubmed.ncbi.nlm.nih.gov/16766240/
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Vitamin D toxicity in the press
14. Oudere persoon overleden na overdosis vitamine D, FAGG waarschuwt voor inname te hoge concentratie. VRT nieuws, Gezondheid. Laurens Dekock, Belga, 17 maart 2023. Accessed 20 March 2023
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