De epifyse (pijnappelklier) is niet de grootste producent van melatonine, wel het spijsverteringsstelsel. Het hormoon dat het lichaam verwittigt dat het donker is, heeft aparte functies in de darmen. Melatonine synchroniseert spijsverteringsprocessen en is werkzaam als antioxidant. Zijn verhouding met de pancreas is al even bijzonder, omdat de pancreas onder invloed staat van melatonine van zowel de epifyse als van de darmen.
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Boyd AD, Brown D et al. Screening for depression, sleep-related disturbances, and anxiety in patients with adenocarcinoma of the pancreas: a preliminary study. ScientificWorldJournal. 2012;2012:650707
Bubenik GA. Thirty four years since the discovery of gastrointestinal melatonin. J Physiol Pharmacol. 2008 Aug;59 Suppl 2:33-51
Celinski K, Konturek PC et al. Effects of melatonin and tryptophan on healing of gastric and duodenal ulcers with Helicobacter pylori infection in humans. J Physiol Pharmacol. 2011 Oct;62(5):521-6
Celinski K, Konturek SJ et al. Melatonin or L-tryptophan accelerates healing of gastroduodenal ulcers in patients treated with omeprazole. J Pineal Res. 2011 May;50(4):389-94
Chandra R, Liddle RA. Neurohormonal regulation of pancreatic secretion. Curr Opin Gastroenterol. 2012 Sep;28(5):483-7
Chojnacki C, Walecka-Kapica E et al. Influence of melatonin on symptoms of irritable bowel syndrome in postmenopausal women. Endokrynol Pol. 2013;64(2):114-20
Chojnacki C, Wisniewska-Jarosinska M et al. Evaluation of melatonin effectiveness in the adjuvant treatment of ulcerative colitis. J Physiol Pharmacol. 2011 Jun;62(3):327-34
Hansen MV, Madsen MT et al. The effect of MELatOnin on Depression, anxietY, cognitive function and sleep disturbances in patients with breast cancer. The MELODY trial: protocol for a randomised, placebo-controlled, double-blinded trial. BMJ Open. 2012 Jan 11;2(1):e000647
Hussain SA, Khadim HM et al. Effects of melatonin and zinc on glycemic control in type 2 diabetic patients poorly controlled with metformin. Saudi Med J. 2006 Oct;27(10):1483-8
Jaworek J, Szklarczyk J et al. Protective effect of melatonin on acute pancreatitis. Int J Inflam. 2012;2012:173675
Kandil TS, Mousa AA et al. The potential therapeutic effect of melatonin in Gastro-Esophageal Reflux Disease. BMC Gastroenterol. 2010 Jan 18;10:7
Lewy AJ, Bauer VK et al. Melatonin treatment of winter depression: a pilot study. Psychiatry Res. 1998 Jan 16;77(1):57-61
Li MD, Li CM, Wang Z. The role of circadian clocks in metabolic disease. Yale J Biol Med. 2012 Sep;85(3):387-401
Lissoni P, Barni S et al. Clinical results with the pineal hormone melatonin in advanced cancer resistant to standard antitumor therapies. Oncology. 1991;48(6):448-50
Lissoni P, Barni S et al. Immunotherapy with subcutaneous low-dose interleukin-2 and the pineal indole melatonin as a new effective therapy in advanced cancers of the digestive tract. Br J Cancer. 1993 Jun;67(6):1404-7
Lissoni P, Brivio F, Fumagalli L et al. Neuroimmunomodulation in medical oncology: application of psychoneuroimmunology with subcutaneous low-dose IL-2 and the pineal hormone melatonin in patients with untreatable metastatic solid tumors. Anticancer Res. 2008 Mar-Apr;28(2B):1377-81
McMullan CJ, Curhan GC et al. Association of nocturnal melatonin secretion with insulin resistance in nondiabetic young women. Am J Epidemiol. 2013 Jul 15;178(2):231-8
McMullan CJ, Schernhammer ES et al. Melatonin secretion and the incidence of type 2 diabetes. JAMA. 2013 Apr 3;309(13):1388-96
Mills E, Wu P et al. Melatonin in the treatment of cancer: a systematic review of randomized controlled trials and meta-analysis. J Pineal Res. 2005 Nov;39(4):360-6
Pereira Rde S. Regression of gastroesophageal reflux disease symptoms using dietary supplementation with melatonin, vitamins and aminoacids: comparison with omeprazole. J Pineal Res. 2006 Oct;41(3):195-200
Rahman SA, Kayumov L et al. Antidepressant action of melatonin in the treatment of Delayed Sleep Phase Syndrome. Sleep Med. 2010 Feb;11(2):131-6
Wang YM, Jin BZ et al. The efficacy and safety of melatonin in concurrent chemotherapy or radiotherapy for solid tumors: a meta-analysis of randomized controlled trials. Cancer Chemother Pharmacol. 2012 May;69(5):1213-20
